HPV16 E6-Activated OCT4 Promotes Cervical Cancer Progression by Suppressing p53 Expression via Co-Repressor NCOR1
Human papillomaviruses (HPV), mainly HPV16 and HPV18, of high-risk classification are involved in cervical cancer carcinogenesis and progression.Octamer-binding transcription factor 4 (OCT4) is a key transcription factor that is increased in various cancer types.Cervical cancer patients with higher levels of OCT4 had worse survival rates.However, t